Autophagy and Loose Skin Summary:
- Wrinkles and loose skin are caused by lack of collagen in the skin.
- Fibroblasts create collagen in the skin.
- Autophagy improves fibroblast health.
What is the best way to reverse aging skin and “erase” wrinkles? Some of the latest science into the subject has to do with the relationship between something called autophagy and loose skin.
Two groundbreaking studies suggest that visible wrinkles could be greatly reduced by activating this critical physiological “recycling” process. It may even have the power to slow down the aging process.
Let’s take a look at autophagy and loose skin, how they relate to each other, and how you can start using autophagy to improve your skin health.
What Causes Wrinkles and Loose Skin?
Before we get into autophagy, we first need to understand the root cause behind wrinkle formation and loose, sagging skin.
After all, if you want to fix something, you first need to understand how it works.
So what is actually going on underneath our skin that causes wrinkles to form around the corners of our eyes, lines around our mouths, and thinner, sagging skin around our necks and cheeks?
The answer has to do with a protein in your skin called collagen.
Collagen is a protein that supports the structure of your skin. It gives youthful skin that tight perkiness.
Collagen is often described like the springs in a mattress: it holds up your skin and gives it that bouncy strength.
Now, the cells in your body that make collagen are called fibroblasts. We know that as we age, our fibroblasts don’t produce as much collagen.
This reduced collagen and the slowing down of skin cell regeneration results in thin, sagging, and wrinkled skin.
But what if you could boost collagen production from the inside out?
In order to do that, you would need to promote fibroblast activity and also improve skin cell regeneration.
It turns out that autophagy could do both of those things simultaneously.
What is Autophagy?
Put simply, autophagy is the body’s recycling program. Autophagy takes place inside your cells.
As your cells operate, they naturally produce waste byproducts. Adding to that, their parts break down and wear out.
Autophagy allows your body to literally digest these byproducts and broken parts and transform them into raw materials that can be used for energy or reused inside the cell.
The Connection Between Autophagy and Loose Skin
So what is the relationship between autophagy and loose skin?
Here’s what the science says about it. In a 2014 study out of Kyushu University in Fukuoka, Japan, researchers found that aging fibroblasts suffer from a decrease in autophagy.
You can imagine these aging fibroblast cells slowly getting clogged with broken parts and waste, grinding their collagen product to a halt.
The researchers concluded that this slowing down of autophagy “leads to deterioration of dermal integrity and skin fragility.”
But an even more enlightening study on the relationship between autophagy and loose skin came out in 2018 from the Department of Dermatology, Incheon St. Mary’s Hospital, College of Medicine.
In this study, the researchers explicitly stated that “Aging accompanies an increase in intra-cellular stress and has significant impact on the skin. Since dermal fibroblasts are a powerful indicator of skin aging, we compared the autophagic activity of human skin fibroblasts between the young and old…”
Now, what they found was that aging fibroblasts experienced “a higher speed and amount of waste production.”
Furthermore, they said that the aging fibroblasts cannot keep up with this increase in cellular waste, “resulting in skin aging.”
But here’s is the most important finding from this study. The researchers said that “autophagy plays a crucial role in counteracting aging, and strategies aimed at its modulation should hold promise for the prevention of skin aging.”
So let’s connect the dots here between autophagy and loose skin.
- Fibroblasts create collagen in the skin. Collagen keeps skin looking young.
- Autophagy lets cells recycle their parts and keep themselves “clean.”
- Aging fibroblasts suffer from decreased autophagy and an increase in waste production.
- This leads to skin aging, skin fragility, and dermal deterioration.
- Autophagy counteracts aging could prevent skin aging.
So if autophagy combats loose skin and skin aging, the next question is: how do you increase autophagy?
How to Increase Autophagy
Autophagy has become one of the hottest topics in the health and fitness fields.
It turns out that autophagy is not just great for preventing loose skin.
Autophagy can also protect you from cardiovascular and neurodegenerative diseases, diabetes, and also fight infections.
There are thousands of scientific articles coming out every year on the health benefits of autophagy.
The clinically studied time period to begin autophagy is usually between 12 and 16 hours.
When your cells get depleted of nutrients for that long, they start breaking down those worn down parts and waste products to create energy for themselves.
But there is also a class of nutrients, vitamins, and minerals that are known as “caloric restriction mimetics.”
As their name suggests, these nutrients mimic the cellular physiological conditions that happen during fasting. You can learn more about what those physiological conditions are by clicking here.
Because fasting for 12 to 16 hours is difficult for many people, these caloric restriction mimetics are very attractive. They could allow you to start autophagy without fasting for quite that long.
Meet the World’s First Autophagy Supplement
Our Autophagy Stack is the world’s very first supplement designed to start autophagy and support your goals of improving loose skin and wrinkles.
Autophagy Stack includes 6 different caloric restriction mimetics that are proven to help induce autophagy without having to fast for long periods of time.
The Autophagy Stack can not only help you with loose skin and wrinkles, but it is also designed to support the other benefits of autophagy including neuro-protection, cardiovascular support, and insulin sensitivity.